How Long Does Lortab Stay In Your System?

Manish Mishra, MBBS

Medically Reviewed By: Manish Mishra, MBBS

on January 25, 2023

Lortab stays in a person’s system for 20 hours after the last dose. Urine drug tests can detect hydrocodone for up to three days after the last dose.

Lortab, a hydrocodone/acetaminophen combination product, stays in your system for less than one day after the last dose. A dose of hydrocodone and acetaminophen stays in your system for about 20 hours and 10 hours, respectively.

Lortab is a brand name prescription drug that can be prescribed for chronic or severe pain relief. Hydrocodone/acetaminophen products such as Lortab, Norco, and Vicodin are Schedule II controlled substances with a high potential for substance abuse.

Drug testing for hydrocodone may be performed by your employer or as part of an opioid addiction treatment program. Drug testing for acetaminophen may be performed in hospital settings, especially in patients showing signs of a drug overdose.

Drug Tests & Detection Times For Lortab

Drug testing for hydrocodone may detect either unchanged hydrocodone or its main metabolite, norhydrocodone. Norhydrocodone is a byproduct of hydrocodone after it is broken down by the body.

Drug testing for acetaminophen is less common, as acetaminophen has a lower abuse potential.

A positive test result for either hydrocodone or acetaminophen may lead to further testing. You may be assessed for opiate withdrawal symptoms or liver damage.

How Long Does Lortab Stay In Your Urine?

Urine tests can detect Lortab for up to 3 days after the last dose. Urine tests can be a common form of opioid drug testing for healthcare providers.

In Ohio, urine testing may also be a standard form of drug testing for employers. Urine tests in the workplace may ensure that each employee can be productive and suitable for employment.

How Long Does Lortab Stay In your Saliva?

Saliva tests can detect hydrocodone and its metabolites for 1 to 3 days after the last dose. Saliva tests can be a convenient, non-invasive testing method for both patients and medical professionals.

Eating and drinking can interfere with the results of a saliva test. You may be advised to avoid food and drink for a short length of time before the test.

How Long Does Lortab Stay In Your Blood?

Blood tests can detect Lortab for up to 1 day after the last dose. Blood tests are accurate, although they are likely more invasive than other forms of testing.

Blood tests may be performed on hospital patients showing side effects of hydrocodone or acetaminophen, such as sedation, drowsiness, or drug cravings.

How Long Does Lortab Stay In Your Hair?

Hair tests can detect hydrocodone for up to 90 days after the last dose.

The long amount of time that hair tests can detect opioid use can be attributed to how hair follicles grow. Hydrocodone can reach hair follicles through the bloodstream, and may remain there as the hair grows.

Half-Life Of Lortab

Half-life is the amount of time it takes for a substance to decrease to half of its peak concentration. After about 5 half-life cycles, most substances are virtually eliminated from the bloodstream, also known as elimination time.

A number of factors that can affect half-life and elimination time, including body fat, frequency of use, The average half-life of the active ingredients in Lortab are:

  • hydrocodone: 4 hours
  • acetaminophen: 1-3 hours

The average elimination time of the active ingredients in Lortab are:

  • hydrocodone: 20 hours
  • acetaminophen: 5-15 hours

A positive drug test for Lortab use may lead to a referral to an addiction treatment program. To find out if our opioid detox, behavioral therapy, and mental health services will work for you or your loved one, please contact Ohio Recovery Center today.

  1. ARUP Laboratories — DRUG PLASMA HALF-LIFE AND URINE DETECTION WINDOW https://www.aruplab.com/files/resources/pain-management/DrugAnalytesPlasmaUrine.pdf
  2. Food and Drug Administration — Norco Drug Label https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/040099Orig1s018lbl.pdf
  3. National Library of Medicine: DailyMed — Label: LORTAB- hydrocodone bitartrate and acetaminophen tablet https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f508d99b-92f7-4dcc-89bb-83d29ed988b3

Written by Ohio Recovery Center Editorial Team

© 2024 Ohio Recovery Center | All Rights Reserved

* This page does not provide medical advice.

Prefer Texting?
We've got you covered.

Receive 24/7 text support right away.
There is no obligation and you can opt out at any time.
chat-header

Sign up for text support

Receive 24/7 text support right away.
There is no obligation and you can opt out at any time.
chat-header
Let us walk you through the treatment process. We're here to help.
For 24/7 Treatment Help:
100% Free & Confidential. Call (419) 904-4158
(419) 904-4158