Percocet Withdrawal Symptoms | Timeline & Detox

Manish Mishra, MBBS

Medically Reviewed By: Manish Mishra, MBBS

on December 13, 2022

Percocet withdrawal symptoms can consist of changes in heart rate and blood pressure, sweating, and tremors. Those experiencing withdrawal symptoms may require detox at a treatment center to receive support, supervision, and safety during withdrawal.

Percocet, or the combination of oxycodone (OxyContin) and acetaminophen (Tylenol), is a prescription opioid medication prescribed to those in need of pain management. 

Those suffering from moderate to severe pain may be prescribed this painkiller, which can lead to opioid withdrawal symptoms when the drug is no longer taken or if the medication is not taken as prescribed.

Percocet Withdrawal Symptoms

As an opioid medication, Percocet works by binding to opioid receptors in the brain, affecting the central nervous system (CNS). This is how Percocet acts as a pain reliever, providing relief and sedation to those in severe pain.

For those who participate in Percocet use and suddenly stop taking the drug, opioid withdrawal symptoms may occur. It is never advised to stop taking medication “cold turkey.”

As stated by the United States Food and Drug Administration (FDA), abrupt discontinuation of the medication may result in withdrawal symptoms. 

The symptoms of withdrawal associated with Percocet include psychological and physical symptoms. Opioid dependence may lead a person to develop cravings for the drug.

Percocet Withdrawal Timeline

Severe symptoms may arise depending on the type of drug abuse that has taken place. However, certain withdrawal symptoms may take place sooner than others.

The First Days Of Withdrawal

According to the National Institute on Drug Abuse (NIDA), withdrawal symptoms may take place 5-8 hours after the last dose has been taken. Some of the symptoms during this stage may consist of body aches and pains, a runny nose, and sweating.

Opioid use may result in withdrawal symptoms which become more severe within the first few days of stopping the medication. During this time, you may experience specific symptoms including:

  • increase in blood pressure and heart rate
  • severe muscle aches
  • sleeping problems
  • fatigue
  • nausea
  • vomiting
  • diarrhea
  • tremors

The Following Weeks

The physical symptoms of Percocet withdrawal may only take place during the first week, although drug cravings are consistently experienced throughout the withdrawal process. In addition to the physical symptoms which occur, there are mental health concerns as well.

For instance, many who suffer from substance use disorders may struggle with depression, suicidal ideations, and other concerning health problems. An important component of treatment is behavioral therapy which can address symptoms of mental illness.

Percocet Detox & Addiction Treatment

Medical detox may be necessary depending on the severity of the drug addiction. Detox typically takes place during the first stages of a treatment program, and may involve tapering the medication to avoid severe withdrawal symptoms.

The detoxification process is a short-term process. During this process, your body will rid itself of unwanted toxins and other substances.

Those who choose detox may also require an inpatient or outpatient treatment program.

Inpatient Treatment

As an inpatient, you’ll have 24/7 access to medical professionals who can provide you with medical care, medication, and assistance. At a residential treatment center in Ohio, you can participate in therapy programs and other treatment options.

Medication-Assisted Treatment

According to the Substance Abuse and Mental Health Services Administration (SAMHSA), a number of medications may be administered to address physical dependence to opioids. These medications consist of buprenorphine, methadone, naloxone, and naltrexone.

If you or a loved one are struggling with drug use, consider Ohio Recovery Center. Our inpatient Percocet addiction treatment options include medication-assisted treatment, medical detox, behavioral therapy, and more.

For additional information, please contact one of our healthcare representatives today.

  1. Drug Enforcement Administration — Oxycodone
  2. Food and Drug Administration — Percocet,040341s013,040434s003lbl.pdf
  3. National Institute on Drug Abuse — What are Prescription Opioids?
  4. National Library of Medicine: MedlinePlus — Oxycodone
  5. National Library of Medicine: StatPearls — Opioid Withdrawal

Written by Ohio Recovery Center Editorial Team

© 2024 Ohio Recovery Center | All Rights Reserved

* This page does not provide medical advice.

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